BDBM173476 US9096606, 13

SMILES COc1ccc2C[C@@H]3[C@]45CC[C@](OC)([C@@H]6Oc1c2[C@]46CC[N+]3(C)CC1CC1)[C@@H](COCc1ccc2ccccc2c1)C5

InChI Key InChIKey=PQFGWRPKZALKDT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173476   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM173476(US9096606, 13)
Affinity DataKi:  165nM ΔG°:  -8.59kcal/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kippa opioid receptor (cloned in house) were prepared by lysing cells in ice cold hypot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM173476(US9096606, 13)
Affinity DataKi:  182nM ΔG°:  -9.96kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for -opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent