BDBM173472 US9096606, 9

SMILES COc3ccc4C[C@@H]7[C@@]26CC[C@@](OC)([C@@H](COc1ccccc1)C2)[C@@H]5Oc3c4[C@@]56CC[N+]7(C)CC8CC8

InChI Key InChIKey=HLOOTFAQODXAHN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173472   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM173472(US9096606, 9)
Affinity DataKi:  348nM ΔG°:  -8.18kcal/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kippa opioid receptor (cloned in house) were prepared by lysing cells in ice cold hypot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM173472(US9096606, 9)
Affinity DataKi:  1.49E+3nM ΔG°:  -8.61kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for -opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent