BDBM173467 US9096606, 4

SMILES CO[C@]13CC[C@@]4(C[C@@H]1COCc2ccc(F)cc2)[C@H]5Cc7ccc(O)c8O[C@@H]3[C@]4(CC[N+]5(C)CC6CC6)c78

InChI Key InChIKey=KDRPLPCXUIBXLY-UHFFFAOYSA-O

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 173467   

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM173467(US9096606, 4)
Affinity DataKi:  0.260nM ΔG°:  -12.1kcal/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human kippa opioid receptor (cloned in house) were prepared by lysing cells in ice cold hypot...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM173467(US9096606, 4)
Affinity DataKi:  9.55nM ΔG°:  -11.9kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand dose-displacement binding assays for -opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.), with 5 mg membrane ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM173467(US9096606, 4)
Affinity DataKi:  175nMpH: 7.4Assay Description:δ-opioid Receptor Binding Assay Procedures were conducted as follows. Radioligand dose-displacement assays used 0.3 nM [3H]-Naltrindole (Perkin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent

TargetOpioid growth factor receptor-like protein 1(Human)
Purdue Pharma

US Patent
LigandPNGBDBM173467(US9096606, 4)
Affinity DataKi: >2.00E+4nM ΔG°: >-5.95kcal/molepH: 7.4 T: 2°CAssay Description:Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Perkin Elmer, Shelton, Conn.) were prepared by l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
US Patent