BDBM173105 US9096589, 5,7-Dimethyl-2-{2-[1-(3-methyl-butyl)-4-thiophen-2-yl-1H-imidazol-2-yl]-ethyl}-imidazo[1,2-a]pyrimidine::US9669029, 26 5,7-Dimethyl-2-{2-[1-(3-methyl-butyl)-4-thiophen-2-yl-1H-imidazol-2-yl]-ethyl}-imidazo[1,2-a]pyrimidine

SMILES CC(C)CCn1cc(nc1CCc1cn2c(C)cc(C)nc2n1)-c1cccs1

InChI Key InChIKey=YAACRQBYHXRYJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173105   

LigandPNGBDBM173105(US9669029, 26 5,7-Dimethyl-2-{2-[1-(3-methyl-butyl...)
Affinity DataIC50: 6.80nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
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LigandPNGBDBM173105(US9669029, 26 5,7-Dimethyl-2-{2-[1-(3-methyl-butyl...)
Affinity DataIC50: 6.80nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
Go to US Patent