BDBM172724 US9096515, 31b::US9296681, 31b

SMILES CCCC(=O)NCCNC(CC(C)C)C1(CCC1)c1ccc(OCC)cc1

InChI Key InChIKey=KESMMXPCOOCEDA-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 172724   

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172724(US9296681, 31b | US9096515, 31b)
Affinity DataKi:  25nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172724(US9296681, 31b | US9096515, 31b)
Affinity DataKi:  25nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172724(US9296681, 31b | US9096515, 31b)
Affinity DataKi:  251nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172724(US9296681, 31b | US9096515, 31b)
Affinity DataKi:  251nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172724(US9296681, 31b | US9096515, 31b)
Affinity DataKi:  4.73E+3nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172724(US9296681, 31b | US9096515, 31b)
Affinity DataKi:  4.73E+3nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent