BDBM172720 US9096515, 12u::US9296681, 12u

SMILES CCOc1ccc(cc1)C1(CCC1)C(CC(C)C)NCCOC(=O)CC

InChI Key InChIKey=GAWYDFHTJQSNCE-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 172720   

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172720(US9296681, 12u | US9096515, 12u)
Affinity DataKi:  5.70nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172720(US9296681, 12u | US9096515, 12u)
Affinity DataKi:  5.70nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172720(US9296681, 12u | US9096515, 12u)
Affinity DataKi:  80.4nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172720(US9296681, 12u | US9096515, 12u)
Affinity DataKi:  80.4nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172720(US9296681, 12u | US9096515, 12u)
Affinity DataKi:  2.34E+3nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172720(US9296681, 12u | US9096515, 12u)
Affinity DataKi:  2.34E+3nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent