BDBM172719 US9096515, 12q::US9296681, 12q

SMILES CCC(=O)OCCNC(CC(C)C)C1(CCC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=XCAMEKYVLTTXGP-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 172719   

TargetSodium-dependent dopamine transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172719(US9296681, 12q | US9096515, 12q)
Affinity DataKi:  7.20nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
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TargetSodium-dependent dopamine transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172719(US9296681, 12q | US9096515, 12q)
Affinity DataKi:  7.20nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172719(US9296681, 12q | US9096515, 12q)
Affinity DataKi:  10.6nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172719(US9296681, 12q | US9096515, 12q)
Affinity DataKi:  10.6nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172719(US9296681, 12q | US9096515, 12q)
Affinity DataKi:  38.2nMAssay Description:The monoamine transporters inhibitory activities of selected compounds cycloalkylmethylamine derivatives comprising Formula (I) are reported herein. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2016
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Reviva Pharmaceuticals

US Patent
LigandPNGBDBM172719(US9296681, 12q | US9096515, 12q)
Affinity DataKi:  38.2nMAssay Description:The compounds were evaluated using well established radioligand binding assays protocols (Galli, A. et al., J. Exp. Biol. 1995, 198, 2197-2212; Giros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2017
Entry Details
Go to US Patent