BDBM172697 US9090628, 357::US9090628, 371

SMILES COc1cc2OCCn3cc(nc3-c2cc1[C@H](C)N1CCN(CC1)C(C)(C)C)-c1nc(C)nn1C(C)C

InChI Key InChIKey=PGCKRQJTWQLDQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 172697   

LigandPNGBDBM172697(US9090628, 371 | US9090628, 357)
Affinity DataIC50: 0.784nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM172697(US9090628, 371 | US9090628, 357)
Affinity DataIC50: 5.30nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent