BDBM172693 US9090628, 353::US9090628, 355

SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(F)c(cc3-c2n1)-c1ccnn1C1CCCN(C1)C(C)(C)CO

InChI Key InChIKey=PXQTVSUZVWYORU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 172693   

LigandPNGBDBM172693(US9090628, 355 | US9090628, 353)
Affinity DataIC50: 0.314nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM172693(US9090628, 355 | US9090628, 353)
Affinity DataIC50: 0.415nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent