BDBM172635 US9090628, 295::US9090628, 302::US9090628, 312::US9090628, 313::US9090628, 329::US9090628, 330::US9090628, 362::US9090628, 363

SMILES CC(C)n1nc(C)nc1-c1cn2CCOc3cc(ccc3-c2n1)-c1cnn(C)c1C1CC(CCO1)N(C)C

InChI Key InChIKey=AYZRGQPKPDHNAX-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 172635   

LigandPNGBDBM172635(US9090628, 330 | US9090628, 363 | US9090628, 362 |...)
Affinity DataIC50: 0.721nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM172635(US9090628, 330 | US9090628, 363 | US9090628, 362 |...)
Affinity DataIC50: 1.65nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM172635(US9090628, 330 | US9090628, 363 | US9090628, 362 |...)
Affinity DataIC50: 0.735nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM172635(US9090628, 330 | US9090628, 363 | US9090628, 362 |...)
Affinity DataIC50: 0.951nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM172635(US9090628, 330 | US9090628, 363 | US9090628, 362 |...)
Affinity DataIC50: 0.864nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM172635(US9090628, 330 | US9090628, 363 | US9090628, 362 |...)
Affinity DataIC50: 0.630nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM172635(US9090628, 330 | US9090628, 363 | US9090628, 362 |...)
Affinity DataIC50: 1.08nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

LigandPNGBDBM172635(US9090628, 330 | US9090628, 363 | US9090628, 362 |...)
Affinity DataIC50: 1.20nMpH: 7.5Assay Description:PI3K enzymatic activity was assayed by measuring the amount of product phosphatidylinositol 3,4,5-phosphate (PIP3) formed from substrate 4,5 phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent