BDBM172416 US9090618, ZA39::US9598411, Ref. No. ZA39

SMILES C1C[C@H]2C[C@H](C[C@@H](C1)N2[C@H]1C[C@@H]2C[C@H](C1)CCCC2)n1c(nc2ccccc12)-c1nnn[nH]1

InChI Key InChIKey=XWEGIPAVEMURDI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 172416   

TargetOpioid growth factor receptor-like protein 1(Human)
Purdue Pharma

US Patent
LigandPNGBDBM172416(US9090618, ZA39 | US9598411, Ref. No. ZA39)
Affinity DataKi:  5.10nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays (screening and dose-displacement) used 0.1 nM [3H]-nociceptin (NEN; 87.7 Ci/mmole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetNociceptin receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM172416(US9090618, ZA39 | US9598411, Ref. No. ZA39)
Affinity DataKi:  5.10nMAssay Description:δ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 &#...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM172416(US9090618, ZA39 | US9598411, Ref. No. ZA39)
Affinity DataKi:  566nMpH: 7.4Assay Description:Radioligand dose displacement assays used 0.4-0.8 nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 μg membrane protein (recombinant kappa opioid re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM172416(US9090618, ZA39 | US9598411, Ref. No. ZA39)
Affinity DataKi:  566nMAssay Description:μ-Opioid Receptor Binding Assay Procedures: Radioligand binding assays were conducted using freshly thawed membranes expressing human μ-rec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent