BDBM1724 3-{[(4R,5S,6S,7R)-4,7-dibenzyl-3-[(3-cyanophenyl)methyl]-5,6-dihydroxy-2-oxo-1,3-diazepan-1-yl]methyl}benzonitrile::Cyclic Urea deriv. 9p

SMILES O[C@@H]1[C@@H](O)[C@@H](Cc2ccccc2)N(Cc2cccc(c2)C#N)C(=O)N(Cc2cccc(c2)C#N)[C@@H]1Cc1ccccc1

InChI Key InChIKey=YHSHWUKUIKBKFJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1724   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Dupont Pharmaceuticals

LigandPNGBDBM1724(3-{[(4R,5S,6S,7R)-4,7-dibenzyl-3-[(3-cyanophenyl)m...)
Affinity DataKi:  3nMAssay Description:Inhibition of HIV protease was measured by assay of the cleavage of a fluorescent peptide substrate. The fluorescent product (2-aminobenzoyl-Ala-Thr-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2004
Entry Details Article
PubMed