BDBM172357 US9090596, 37a::US9090596, 37b

SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3cc(C)co3)C3(C)COC3)c(=O)c2=O)c1O

InChI Key InChIKey=PCXDKTNTSYUMHN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 172357   

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM172357(US9090596, 37b | US9090596, 37a)
Affinity DataIC50: 827nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM172357(US9090596, 37b | US9090596, 37a)
Affinity DataIC50: 7.69E+3nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM172357(US9090596, 37b | US9090596, 37a)
Affinity DataIC50: 32nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent

TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM172357(US9090596, 37b | US9090596, 37a)
Affinity DataIC50: 207nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent