BDBM172340 US9090596, 20

SMILES Cc1ccc(o1)C(Nc1c(Nc2cccnc2O)c(=O)c1=O)C1(C)COC1

InChI Key InChIKey=QRWLFDDWLCJPJQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 172340   

TargetC-X-C chemokine receptor type 1(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM172340(US9090596, 20)
Affinity DataIC50: 6.62E+3nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
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TargetC-X-C chemokine receptor type 2(Human)
Galderma Research & Development

US Patent
LigandPNGBDBM172340(US9090596, 20)
Affinity DataIC50: 335nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2016
Entry Details
Go to US Patent