BDBM17193 2-(4-{[3-(4-{[(2-methylphenyl)carbamoyl]amino}phenyl)-2-oxo-1,2-dihydropyridin-1-yl]methyl}phenyl)acetic acid::Pyridone analog, 14

SMILES Cc1ccccc1NC(=O)Nc1ccc(cc1)-c1cccn(Cc2ccc(CC(O)=O)cc2)c1=O

InChI Key InChIKey=YDSHGKWTPATILZ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17193   

TargetIntegrin alpha-4/beta-1 [T112H](Human)
Glaxosmithkline

LigandPNGBDBM17193(2-(4-{[3-(4-{[(2-methylphenyl)carbamoyl]amino}phen...)
Affinity DataKi:  251nM ΔG°:  -8.91kcal/molepH: 7.5 T: 2°CAssay Description:J6 cells (1 million cells/well) were allowed to coat wheat germ agglutinin coated SPA beads (Amersham, 1 mg/well) in assay buffer. Tritiated 3H Stand...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2007
Entry Details Article
PubMed