BDBM1719 US8470837, 23
SMILES Cn1c2ncn(C[C@@H](O)CO)c(=O)c2c(Nc2ccc(NCS(C)(=O)=O)cc2F)c(F)c1=O
InChI Key InChIKey=BYCARCPDPRTESX-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 1719
TargetDual specificity mitogen-activated protein kinase kinase 1 [2-31,52-393,S218E,S222D](Human)
Takeda Pharmaceutical
US Patent
Takeda Pharmaceutical
US Patent
Affinity DataIC50: 16nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair