BDBM1717 US8470837, 21
SMILES Cn1c2ncn(C[C@H](O)CO)c(=O)c2c(Nc2ccc(cc2F)C#N)c(F)c1=O
InChI Key InChIKey=SIQPPFUZXXNPJR-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 1717
TargetDual specificity mitogen-activated protein kinase kinase 1 [2-31,52-393,S218E,S222D](Human)
Takeda Pharmaceutical
US Patent
Takeda Pharmaceutical
US Patent
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair