BDBM169603 US9079880, 136

SMILES O=C(Nc1nc2CC[C@@H](Cc2s1)N1CCOCC1)c1cccc(c1)[C@H]1CCCN1C(=O)c1csc(n1)-c1cccnc1

InChI Key InChIKey=NBALCAPIKLXBDV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 169603   

TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM169603(US9079880, 136)
Affinity DataIC50: 2.60nMpH: 7.5Assay Description:The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
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TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM169603(US9079880, 136)
Affinity DataIC50: 6.90nMpH: 7.2Assay Description:This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent