BDBM169541 US9079880, 74

SMILES CN1CCc2nc(NC(=O)c3cccc(c3)[C@H]3CCCN3C(=O)c3cn4cc(ccc4n3)C(N)=O)sc2C1

InChI Key InChIKey=ISODQVKLZILGBD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 169541   

TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM169541(US9079880, 74)
Affinity DataIC50: 2.5nMpH: 7.5Assay Description:The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM169541(US9079880, 74)
Affinity DataIC50: 7.40nMpH: 7.2Assay Description:This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent