BDBM168605 US9073939, 4

SMILES Cc1noc2NC(C)=C([N+]#[C-])C(c12)c1cc2c(C)n[nH]c2cc1F

InChI Key InChIKey=MQFDMOPYKXZYLJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 168605   

TargetHepatocyte growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM168605(US9073939, 4)
Affinity DataIC50: 23nMpH: 7.0 T: 2°CAssay Description:Recombinant human c-Met protein (Invitrogen, Carlsbad, Calif., USA) is used. As substrate for the kinase reaction the peptide KKKSPGEYVNIEFG (JPT, Ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent

TargetHepatocyte growth factor receptor(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM168605(US9073939, 4)
Affinity DataIC50: 126nMpH: 7.5 T: 2°CAssay Description:The N-terminally His6-tagged recombinant kinase domain of the human c-Met (amino acids 960-1390), expressed in insect cells (SF21) and purified by Ni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent