BDBM168111 US9073931, E23a

SMILES CC(C)[C@H]1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(c(n1)C(F)(F)F)C(C)(C)O

InChI Key InChIKey=LOFRRPNYSLDHRM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 168111   

TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM168111(US9073931, E23a)
Affinity DataKi:  21nM ΔG°:  -10.5kcal/moleT: 2°CAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent

TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM168111(US9073931, E23a)
Affinity DataKi:  237nM ΔG°:  -9.03kcal/moleT: 2°CAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent