BDBM168072 US9073931, E1

SMILES CC(C)C1N(CCn2c1nc1ccc(cc21)S(C)(=O)=O)c1ncc(C(C)=O)c(n1)C(F)(F)F

InChI Key InChIKey=UVRFHLLVIGMMMM-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 168072   

TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM168072(US9073931, E1)
Affinity DataKi:  191nM ΔG°:  -9.16kcal/moleT: 2°CAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent

TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM168072(US9073931, E1)
Affinity DataKi:  1.40E+3nM ΔG°:  -7.98kcal/moleT: 2°CAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2016
Entry Details
Go to US Patent