BDBM16791 3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-methyl-1H-pyrazolo[3,4-c]pyridin-5-yl}pyridine::pyrazolopyridine analog, 9i

SMILES Cc1n[nH]c2cnc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1

InChI Key InChIKey=BJQFSJIVYSQLSX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16791   

LigandPNGBDBM16791(3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-methyl-1H-py...)
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
LigandPNGBDBM16791(3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-methyl-1H-py...)
Affinity DataIC50: 32nMAssay Description:The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2007
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM16791(3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-methyl-1H-py...)
Affinity DataIC50: 14nMAssay Description:Inhibition of AktMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMed