BDBM16750 2,2,2-trifluoroacetic acid; 2-oxo-N-[5-phenyl-2-(piperazin-1-yl)phenyl]-2H-chromene-3-carboxamide::CHEMBL1164612::Coumarin Compound, 11d

SMILES O=C(Nc1cc(ccc1N1CCNCC1)-c1ccccc1)c1cc2ccccc2oc1=O

InChI Key InChIKey=KHDMWLZSDRWJGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16750   

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16750(CHEMBL1164612 | 2,2,2-trifluoroacetic acid; 2-oxo-...)
Affinity DataIC50: 580nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16750(CHEMBL1164612 | 2,2,2-trifluoroacetic acid; 2-oxo-...)
Affinity DataIC50: 580nMAssay Description:Inhibition of BACE1 after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed