BDBM167421 US9073893, 21

SMILES Cn1n(C2CCNCC2)c(=O)c2c(cc(F)cc12)C(N)=O

InChI Key InChIKey=LIGDLZRFUNWVFK-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 167421   

TargetPoly [ADP-ribose] polymerase 1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167421(US9073893, 21)
Affinity DataKd: <10nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent

TargetPoly [ADP-ribose] polymerase 2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167421(US9073893, 21)
Affinity DataKd:  70nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent

TargetProtein mono-ADP-ribosyltransferase PARP3 [R100H](Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM167421(US9073893, 21)
Affinity DataKd:  40nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2016
Entry Details
Go to US Patent