BDBM16742 Coumarin Compound, 9e::N-{5-bromo-2-[4-(2-hydroxyethyl)piperazin-1-yl]phenyl}-2-oxo-2H-chromene-3-carboxamide

SMILES OCCN1CCN(CC1)c1ccc(Br)cc1NC(=O)c1cc2ccccc2oc1=O

InChI Key InChIKey=OIXRHSBEQHAKPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16742   

TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16742(N-{5-bromo-2-[4-(2-hydroxyethyl)piperazin-1-yl]phe...)
Affinity DataIC50: 630nMAssay Description:These experiments have been preformed using BACE-1 FRET assay kit (PanVera Corporation, Madison, WI), using a multiwell spectrofluorometer instrument...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2007
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Universite De La Mediterranee

LigandPNGBDBM16742(N-{5-bromo-2-[4-(2-hydroxyethyl)piperazin-1-yl]phe...)
Affinity DataIC50: 630nMAssay Description:Inhibition of BACE1 after 2 hrs by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed