BDBM16651 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-heptadecafluoro-N-(4-sulfamoylphenyl)nonanamide::CHEMBL281794::aromatic sulfonamide compound 16

SMILES NS(=O)(=O)c1ccc(NC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

InChI Key InChIKey=HYDXHEWUVUJPKB-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 16651   

TargetCarbonic anhydrase 5A, mitochondrial(Mouse)
Universita Degli Studi Di Firenze

LigandPNGBDBM16651(CHEMBL281794 | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-h...)
Affinity DataKi:  13nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16651(CHEMBL281794 | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-h...)
Affinity DataKi:  66nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16651(CHEMBL281794 | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-h...)
Affinity DataKi:  66nMAssay Description:Inhibition of human recombinant carbonic anhydrase II (CA2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi Di Firenze

LigandPNGBDBM16651(CHEMBL281794 | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-h...)
Affinity DataKi:  850nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi Di Firenze

LigandPNGBDBM16651(CHEMBL281794 | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-h...)
Affinity DataKi:  850nMAssay Description:Inhibition of bovine carbonic anhydrase IV (CA4) from bovine lung microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16651(CHEMBL281794 | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-h...)
Affinity DataKi:  1.40E+3nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16651(CHEMBL281794 | 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-h...)
Affinity DataKi:  1.40E+3nMAssay Description:Inhibition of human recombinant carbonic anhydrase I (CA1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed