BDBM1665 CHEMBL1684061::US8470837, 2

SMILES Cn1c2ncn(CCO)c(=O)c2c(Nc2ccc(I)cc2F)cc1=O

InChI Key InChIKey=BXWCMILXGIDJLA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1665   

LigandPNGBDBM1665(CHEMBL1684061 | US8470837, 2)
Affinity DataIC50: 10nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds relative to MEK1 or MEK2 may be determined using a black 384-well-plate format under the following reaction co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
Go to US Patent

LigandPNGBDBM1665(CHEMBL1684061 | US8470837, 2)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of MEK1 by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed