BDBM16647 2-methyl-N-(4-sulfamoylphenyl)propanamide::4-Isobutanamido-benzenesulfonamide::CHEMBL23417::aromatic sulfonamide compound 12

SMILES CC(C)C(=O)Nc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=VVHPZBGPXIXCQI-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 16647   

TargetCarbonic anhydrase 12(Human)
Università

Curated by ChEMBL
LigandPNGBDBM16647(CHEMBL23417 | 2-methyl-N-(4-sulfamoylphenyl)propan...)
Affinity DataKi:  138nMAssay Description:Inhibitory activity against human Carbonic anhydrase XII (hCA XII)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Università

Curated by ChEMBL
LigandPNGBDBM16647(CHEMBL23417 | 2-methyl-N-(4-sulfamoylphenyl)propan...)
Affinity DataKi:  139nMAssay Description:Inhibitory activity against human Carbonic anhydrase IX (hCA IX)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Mouse)
Universita Degli Studi Di Firenze

LigandPNGBDBM16647(CHEMBL23417 | 2-methyl-N-(4-sulfamoylphenyl)propan...)
Affinity DataKi:  233nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16647(CHEMBL23417 | 2-methyl-N-(4-sulfamoylphenyl)propan...)
Affinity DataKi:  258nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16647(CHEMBL23417 | 2-methyl-N-(4-sulfamoylphenyl)propan...)
Affinity DataKi:  258nMAssay Description:Inhibitory activity against human Carbonic anhydrase II (hCA II)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Bovine)
Universita Degli Studi Di Firenze

LigandPNGBDBM16647(CHEMBL23417 | 2-methyl-N-(4-sulfamoylphenyl)propan...)
Affinity DataKi:  2.84E+3nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16647(CHEMBL23417 | 2-methyl-N-(4-sulfamoylphenyl)propan...)
Affinity DataKi:  2.35E+4nM ΔG°:  -6.31kcal/molepH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Universita Degli Studi Di Firenze

LigandPNGBDBM16647(CHEMBL23417 | 2-methyl-N-(4-sulfamoylphenyl)propan...)
Affinity DataKi:  2.35E+4nMAssay Description:Inhibitory activity against human Carbonic anhydrase I (hCA I)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed