BDBM166439 US9073833, Sivelestat
SMILES CC(C)(C)C(=O)Oc1ccc(cc1)S(=O)(=O)Nc1ccccc1C(O)=NCC(O)=O
InChI Key InChIKey=BTGNGJJLZOIYID-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 166439
Affinity DataIC50: 3.38E+5nMpH: 7.5Assay Description:Compound (1) was mixed with 50 uL of buffer C [containing 100 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES, pH 7.5), 500 mM NaCl, 10%...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+4nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair