BDBM166433 US9073833, 1

SMILES C\C(=N/O)c1ccccc1NS(=O)(=O)c1ccc(OC(=O)C(C)(C)C)cc1

InChI Key InChIKey=MSIGLHAWDSGRGI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 166433   

TargetNeutrophil elastase(Human)
Chang Gung University

US Patent
LigandPNGBDBM166433(US9073833, 1)
Affinity DataIC50: 2.22E+5nMpH: 7.5Assay Description:Compound (1) was mixed with 50 uL of buffer C [containing 100 mM 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES, pH 7.5), 500 mM NaCl, 10%...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
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TargetNeutrophil elastase(Human)
Chang Gung University

US Patent
LigandPNGBDBM166433(US9073833, 1)
Affinity DataIC50: 30nMT: 2°CAssay Description:Each of Compounds (1) to (6) was dissolved in 100% DMSO so as to obtain stock to compound solutions with concentrations of 0.01, 0.03, 0.1, 0.3, 1, 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
Go to US Patent

TargetNeutrophil elastase(Human)
Chang Gung University

US Patent
LigandPNGBDBM166433(US9073833, 1)
Affinity DataIC50: 5.13E+4nMpH: 7.4Assay Description:Each of Compounds (1) to (7) was added into 50 μL buffer A (containing 20 mM Tris-HCl (pH 7.4), 0.1% NaN3 and 5 mM CaCl2) to obtain compound sol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
Go to US Patent