BDBM165399 US8168651, Compound TABLE 16.67::US9062043, Table 13, Compound 67::US9062043, Table 20b, Compound 31

SMILES Nc1ncc2c3ccc(cc3nc(Nc3ccc(F)c(Cl)c3)c2n1)C(O)=O

InChI Key InChIKey=DXIOENHPVMRFQA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 165399   

TargetCasein kinase II subunit alpha(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM165399(US9062043, Table 20b, Compound 31 | US9062043, Tab...)
Affinity DataIC50: 44nMpH: 7.4Assay Description:The human leukemia Jurkat T-cell line was maintained in RPMI 1640 (Cambrex) supplemented with 10% fetal calf serum and 50 ng/ml Geutamycin. Before tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
Go to US Patent

TargetCasein kinase II subunit alpha(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM165399(US9062043, Table 20b, Compound 31 | US9062043, Tab...)
Affinity DataIC50: 7nMpH: 7.2Assay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
Go to US Patent

TargetCasein kinase II subunit alpha(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM165399(US9062043, Table 20b, Compound 31 | US9062043, Tab...)
Affinity DataIC50: 7nMAssay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent