BDBM16530 2-arylpyridazin-3-one, 36::N-{3-[(2-chlorophenyl)[1-(2-chlorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]amino]propyl}-4-(trifluoromethyl)cyclohexane-1-carboxamide

SMILES FC(F)(F)C1CCC(CC1)C(=O)NCCCN(c1ccc(=O)n(n1)-c1ccccc1Cl)c1ccccc1Cl

InChI Key InChIKey=DDKMTWFWDUOVDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16530   

TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandPNGBDBM16530(N-{3-[(2-chlorophenyl)[1-(2-chlorophenyl)-6-oxo-1,...)
Affinity DataIC50: 20nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

LigandPNGBDBM16530(N-{3-[(2-chlorophenyl)[1-(2-chlorophenyl)-6-oxo-1,...)
Affinity DataIC50: 2nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed