BDBM16522 2-arylpyridazin-3-one, 28::6-[(3-aminopropyl)(2-chlorophenyl)amino]-2-(2-chlorophenyl)-2,3-dihydropyridazin-3-one

SMILES NCCCN(c1ccc(=O)n(n1)-c1ccccc1Cl)c1ccccc1Cl

InChI Key InChIKey=APBVMOUFGHLMMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16522   

TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandPNGBDBM16522(6-[(3-aminopropyl)(2-chlorophenyl)amino]-2-(2-chlo...)
Affinity DataIC50: 197nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

LigandPNGBDBM16522(6-[(3-aminopropyl)(2-chlorophenyl)amino]-2-(2-chlo...)
Affinity DataIC50: 211nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed