BDBM16517 2-(2-chlorophenyl)-6-[(2-fluorophenyl)sulfanyl]-2,3-dihydropyridazin-3-one::2-arylpyridazin-3-one, 20

SMILES Fc1ccccc1Sc1ccc(=O)n(n1)-c1ccccc1Cl

InChI Key InChIKey=QQEWAIUOEYEOLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16517   

TargetMitogen-activated protein kinase 14(Mouse)
Merck Research Laboratories

LigandPNGBDBM16517(2-(2-chlorophenyl)-6-[(2-fluorophenyl)sulfanyl]-2,...)
Affinity DataIC50: 140nMpH: 7.0 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Mouse)
Merck Research Laboratories

LigandPNGBDBM16517(2-(2-chlorophenyl)-6-[(2-fluorophenyl)sulfanyl]-2,...)
Affinity DataIC50: 450nMAssay Description:The biochemical activity of compounds was determined by incubation with p38 enzyme, and substrates in the presence ATP/[gamma-33P] ATP. After the rea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed