BDBM16456 6-(1-benzofuran-2-sulfonyl)-2,3-dihydropyridazin-3-one::CHEMBL241777::Heterocyclic Sulfonylpyridazinone, 19h::benzofuran, 22

SMILES O=c1ccc(n[nH]1)S(=O)(=O)c1cc2ccccc2o1

InChI Key InChIKey=RBZSSTPBYFHRSR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16456   

LigandPNGBDBM16456(CHEMBL241777 | Heterocyclic Sulfonylpyridazinone, ...)
Affinity DataIC50: 150nMAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2007
Entry Details Article
PubMed
LigandPNGBDBM16456(CHEMBL241777 | Heterocyclic Sulfonylpyridazinone, ...)
Affinity DataIC50: 150nMpH: 7.0 T: 2°CAssay Description:The activity of the enzyme was determined spectrophotometrically by monitoring the change in absorbance at 340 nm, which is due to the disappearance ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2007
Entry Details Article
PubMed
LigandPNGBDBM16456(CHEMBL241777 | Heterocyclic Sulfonylpyridazinone, ...)
Affinity DataIC50: 150nMAssay Description:Inhibition of aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed