BDBM164393 US9669029, 96 8-Methoxy-5-methyl-2-[2-(1-prop-2-ynyl-4-thiophen-2-yl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyridine

SMILES COC1=CC=C(C)N2N=C(CCc3nc(cn3CC#C)-c3cncs3)NC12

InChI Key InChIKey=CCDATKHIJBEXOS-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164393   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Human)
H. Lundbeck

US Patent

LigandBDBM164393(US9669029, 96 8-Methoxy-5-methyl-2-[2-(1-prop-2-yn...)Copy SMILESCopy InChI

Affinity DataIC50: 4.10nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/19/2018
Entry Details
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