BDBM16435 5-(1,2-dithiolan-3-yl)pentanamide::5-(dithiolan-3-yl)pentanamide::D,L-Lipoamide::Thioctamide

SMILES NC(=O)CCCCC1CCSS1

InChI Key InChIKey=FCCDDURTIIUXBY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 16435   

TargetTAR DNA-binding protein 43(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM16435(5-(1,2-dithiolan-3-yl)pentanamide | Thioctamide | ...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of TDP-43 (unknown origin) binding to RNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Medical College of Wiscosin

LigandPNGBDBM16435(5-(1,2-dithiolan-3-yl)pentanamide | Thioctamide | ...)
Affinity DataKi:  8.60E+4nM ΔG°:  -5.54kcal/molepH: 7.0 T: 2°CAssay Description:The production of NADPH from NADP+ and benzyl alcohol and xylitol was monitored by an increase in NADPH fluorescence (ex: 340 nm; em: 460 nm) using a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2007
Entry Details Article
PubMed