BDBM164290 US9669029, 40 5-Methyl-2-[2-(4-thiophen-3-yl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyridine

SMILES Cc3cccc4nc(CCc2ncc(c1ccsc1)[nH]2)nn34

InChI Key InChIKey=MPQFIYFGZQYJIQ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164290   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Human)
H. Lundbeck

US Patent

LigandBDBM164290(US9669029, 40 5-Methyl-2-[2-(4-thiophen-3-yl-1H-im...)Copy SMILESCopy InChI

Affinity DataIC50: 5.70nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In Depth
Date in BDB:
5/19/2018
Entry Details
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