BDBM164285 US9669029, 35 (S)-2-{2-[2-(5-Methyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-ethyl]-4-thiophen-2-yl-imidazol-1-yl}-propan-1-ol
SMILES CC[C@@H](O)n1cc(nc1CCC1=NN2C(N1)C=CC=C2C)-c1cccs1
InChI Key InChIKey=IXRODGHPIKKNFH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 164285
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Human)
H. Lundbeck
US Patent
H. Lundbeck
US Patent
Affinity DataIC50: 6.40nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair