BDBM164284 US9669029, 34 8-Methyl-2-[2-(4-thiophen-2-yl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyridine

SMILES CC1=CC=CN2N=C(CCc3nc(c[nH]3)-c3cccs3)NC12

InChI Key InChIKey=VMWIPOCRLILPQY-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164284   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779](Human)
H. Lundbeck

US Patent

LigandBDBM164284(US9669029, 34 8-Methyl-2-[2-(4-thiophen-2-yl-1H-im...)Copy SMILESCopy InChI

Affinity DataIC50: 0.990nMT: 2°CAssay Description:The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/19/2018
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL