BDBM163717 5-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-3-phenyl-4,5-dihydro-1,2,4-triazin-6(1H)-one (16)

SMILES Clc1cccc(N2CCN(CCCCC3NC(=NNC3=O)c3ccccc3)CC2)c1Cl

InChI Key InChIKey=IWSOWSCXJKNBJL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163717   

Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

LigandPNGBDBM163717(5-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-...)
Affinity DataKi:  16nM ΔG°:  -10.6kcal/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University Medical College

LigandPNGBDBM163717(5-{4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl}-...)
Affinity DataKi:  70nM ΔG°:  -9.75kcal/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed