BDBM163713 5-{4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl}-3-phenyl-4,5-dihydro-1,2,4-triazin-6(1H)-one (12)

SMILES COc1ccccc1N1CCN(CCCCC2NC(=NNC2=O)c2ccccc2)CC1

InChI Key InChIKey=JDBGOUBLTIMSSY-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163713   

Target5-hydroxytryptamine receptor 1A(Human)
Jagiellonian University Medical College

LigandPNGBDBM163713(5-{4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl}-3-p...)
Affinity DataKi:  9nM ΔG°:  -11.0kcal/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

LigandPNGBDBM163713(5-{4-[4-(2-Methoxyphenyl)piperazin-1-yl]butyl}-3-p...)
Affinity DataKi:  27nM ΔG°:  -10.3kcal/moleT: 2°CAssay Description:All assays were incubated in a total volume of 200 mL in 96-well microtiter plates for 1 h at 37 °C, except for 5-HT1ARs which were incubated at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed