BDBM163701 N-[5-({4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}carbamoyl)-2-methylphenyl]-5-(thiophen-2-yl)pyridine-3-carboxamide (6)

SMILES CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)c4cncc(c4)-c4cccs4)c3)cc2C(F)(F)F)CC1

InChI Key InChIKey=HYWXBDQAYLPMIX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 163701   

TargetDiscoidin domain-containing receptor 2(Human)
Dana-Farber Cancer Institute

LigandPNGBDBM163701(N-[5-({4-[(4-ethylpiperazin-1-yl)methyl]-3-(triflu...)
Affinity DataIC50: 51nMAssay Description:The enzymatic activities SRC are tested in Z'-Lyte assays with ATP concentrations of Km (50 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Dana-Farber Cancer Institute

LigandPNGBDBM163701(N-[5-({4-[(4-ethylpiperazin-1-yl)methyl]-3-(triflu...)
Affinity DataIC50: 14nMAssay Description:The enzymatic activities SRC are tested in Z'-Lyte assays with ATP concentrations of Km (50 uM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2016
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM163701(N-[5-({4-[(4-ethylpiperazin-1-yl)methyl]-3-(triflu...)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed