BDBM163638 1(2Fluorophenyl)3(2hydroxyethyl)3[(6methyl2oxo1,2dihydroquinolin3yl)methyl]thiourea (Inh 3)

SMILES Cc1ccc2[nH]c(=O)c(CN(CCO)C(=S)Nc3ccccc3F)cc2c1

InChI Key InChIKey=WPRDQOPGGXWYOO-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 163638   

TargetBeta-glucuronidase(Escherichia coli (strain K12))
University of North Carolina at Chapel Hill

LigandPNGBDBM163638(1(2Fluorophenyl)3(2hydroxyethyl)3[(6methyl2oxo1,2d...)
Affinity DataKi:  680nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed
TargetBeta-galactosidase [V151I,I185V](Clostridium perfringens)
University of North Carolina at Chapel Hill

LigandPNGBDBM163638(1(2Fluorophenyl)3(2hydroxyethyl)3[(6methyl2oxo1,2d...)
Affinity DataKi:  7.80E+3nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed
TargetBeta-galactosidase(Streptococcus agalactiae (Firmicutes))
University of North Carolina at Chapel Hill

LigandPNGBDBM163638(1(2Fluorophenyl)3(2hydroxyethyl)3[(6methyl2oxo1,2d...)
Affinity DataKi:  1.10E+4nMAssay Description:Reactions were conducted similarly to the kinetic assays but the reaction consisted of 10 µL assay buffer, 5 µL inhibitor solution, 5 µL of 10 nM enz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2016
Entry Details Article
PubMed