BDBM163245 US9062045, Reference Example No. 66

SMILES Cn1cc(cn1)-c1cnc2ccc(Sc3nnc4c(F)cc(cn34)-c3cnn(C)c3)cc2c1

InChI Key InChIKey=FKJHSOOOSXHVNK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 163245   

TargetHepatocyte growth factor receptor(Human)
Novartis

US Patent
LigandPNGBDBM163245(US9062045, Reference Example No. 66)
Affinity DataIC50: 3nMAssay Description:The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent

LigandPNGBDBM163245(US9062045, Reference Example No. 66)
Affinity DataIC50: 3.00E+4nMAssay Description:The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent