BDBM163037 US9061041, Compound C

SMILES CCOc1nc(N)nc2n(cnc12)[C@@H]1O[C@@H]2COP(=O)(OC2[C@@]1(C)F)C(C)C

InChI Key InChIKey=LZAMBKJSMJQLGV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 163037   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM163037(US9061041, Compound C)
Affinity DataKi:  30nM ΔG°:  -10.3kcal/molepH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent