BDBM162876 US9056859, 217

SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCN(C2CC12)C(=O)Cc1ccc(nc1)-n1cnnn1

InChI Key InChIKey=AUKXRHFMGMQRFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162876   

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162876(US9056859, 217)
Affinity DataIC50: 56nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent