BDBM162875 US9056859, 177

SMILES C[C@H]1Cc2cc(CCN3CCN(CC3)C(=O)C3CCc4nc(ccc34)-n3cnnn3)ccc2C(=O)O1

InChI Key InChIKey=USJYUQVZKANXEJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 162875   

TargetATP-sensitive inward rectifier potassium channel 1(Rat)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM162875(US9056859, 177)
Affinity DataIC50: 100nMpH: 7.4Assay Description:Block of Kir1.1 (ROMKI) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks Qu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
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