BDBM162805 US9056843, 96

SMILES FC(F)(F)c1nc(no1)-c1ccc(cc1)S(=O)(=O)Nc1ccccc1

InChI Key InChIKey=SIAORXMCCJMMQI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 162805   

TargetHistone deacetylase 1(Human)
Novartis

US Patent
LigandPNGBDBM162805(US9056843, 96)
Affinity DataIC50: 7.00E+3nMpH: 8.0 T: 2°CAssay Description:A similar assay procedure as described in Test 2 was used for HDAC1. Human recombinant full length HDAC1 expressed in a baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent

TargetHistone deacetylase 4(Human)
Novartis

US Patent
LigandPNGBDBM162805(US9056843, 96)
Affinity DataIC50: 96nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Novartis

US Patent
LigandPNGBDBM162805(US9056843, 96)
Affinity DataIC50: 400nMpH: 8.0 T: 2°CAssay Description:A similar assay procedure as described in Test 2 was used for HDAC6. Human recombinant full length HDAC6 expressed in a baculovirus expression system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2016
Entry Details
Go to US Patent